2025
Toward Universal Blood: CRISPR Screens to Enable Scalable RBC Manufacturing.
Collaborators: Dr. Kyle Cromer and Dr. Brian Shy
To Test the Mechanisms and the Efficacy of Allogeneic Bone Marrow Derived MSCs in a Mouse Model Hypo-Inflammatory ARDS.
Collaborators: Dr. Ruriko Watanabe, Dr. Anna Krasnodembskaya, Dr. Huimin Geng, Dr. Mazharul Maishan, and Dr. Michael Matthay
Designer Adipose Tissue: A Novel Stem Cell Theraрy Strategy for Osteoarthritis
Collaborators: Dr. Kelsey Collins, Dr. Edward Hsiao, and Dr. Kyle Cromer
Spatial Transcriptomic and Proteomic Profiling to Identify Biomarkers of Lung Injury and MSC Therapу Responses in Hypo- and Hyper-inflammatory ARDS
Collaborators: Dr. Huimin Geng and Dr. Ruriko Watanabe
The Interaction Between Endothelium and the Blood Components in Transfusion Responsible for Hemostasis.
Collaborators: Dr. Alison Nair, Dr. Ernest "Gene" Moore, and Scientist Mr. Dallas Vanderheyden
2024
Intranasal Delivery of Human Placenta Mesenchymal Stem Cell Extracellular Vesicles (PMSC-EVs) to Treat Newborn Brain Injury
Collaborators: Dr. Emin Maltepe & Dr. Aijun Wang
The Platelet Function, Transcriptome, and Proteome in Platelet-Rich Plasma for Intra-Articular Therapy in Knee Osteoarthritis: A Pilot Characterization of Platelet Biology for Advancing Regenerative Transfusion Medicine
Collaborators: Drs. Lucy Kornblith, Anthony Luke, Saul Villeda & Roland Bainton
To Test the Efficacy of Allogeneic Bone Marrow Derived MSCs in a Mouse Model of Hyper- and Hypo-Inflammatory ARDS
Collaborators: Drs. Michael Matthay & Carolyn Calfee
Development of a Novel “in-line” Manufacturing method for the Rapid, Cost-Effective, and “off-the-shelf” Production of Cellular Therapeutics
Collaborators: Drs. Omar Khan, Brian Shy, Christopher Dvorak & Julia Chu
Does Pathogen Inactivation Change the Inflammatory Profile of Transfused Platelets?
Collaborators: Drs. Philip Norris, Satish Pillai, Larry Corash, & all Dept. of Laboratory Medicine